Matthew Mifsud, MD

Surgical Oncology
Matthew Mifsud image
4.8 out of 5
372 ratings, 67 comments
13330 USF Laurel Drive, Tampa, FL 33612
See Location
Office Number
813-821-8012
Fax Number
813-821-9702
New Patient Visits
As a head and neck surgical oncologist, my major focus is the treatment within the head and neck region, affecting the face, neck, mouth and throat. At USF, I help lead a multidisciplinary team of medical professionals, that develop individualized cancer treatment plans, for each of our patients.





I have extensive surgical training and experience, which includes advanced subspecialization within my field of otolaryngology. This allows me to perform a wide array of surgical procedures and particularly focus on reconstructive surgery. This entails taking body parts from one area and transplanting them into the head and neck. This helps maintain a more normal physical appearance and optimizes speech/swallowing function, which can be impacted by cancer or other maladies. I'm able to not only treat a person's disease, but also help to optimize their quality of life long after treatment is complete.





In addition to cancer, I also focus on other complex head and neck conditions, such as those affecting the salivary glands, thyroid, and trachea. At USF, I also engage in various teaching and research activities, which enhance my ability to provide state-of-the-art care to all my patients.


About Matthew

Patient Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
4.8 out of 5
372 ratings,
67 reviews
3/15/2026
Good
3/13/2026
Dr spent maybe 5 mins with me.
3/12/2026
Good
2/28/2026
The medical doctor spent 5 mins in the room with me after a prolong wait and explained that he did not have "time" and I should not have been scheduled for a procedure (biopsy) on the first visit. The rheumatologist requested only a biopsy to rule out a medical disease. The nurse/tech confirmed prior to the doctor entering the room that my appt was for a biopsy. This decision to not perform the biopsy has delayed my care, completely disregarded the importance of my time and health because the doctor did not have time to do his job.
2/27/2026
Visit was fairly quick. No real concerns to discuss. Another followup visit in 6 months.
2/18/2026
Dr. Mifsud and his team are great. Always polite, always attentive.
2/18/2026
Dr. Mifsud is an outstanding doctor and is very helpful.
1/31/2026
Both Dr. Mifsud and his PA explained everything from diagnosis and what would happen during surgery and post. Excellent job calming my fears
1/30/2026
Dr. Mifsud is, without a doubt, the most communicative doc I've ever visited. Clear answers, patient, a good listener, and clearly very smart. Highly recommend.
1/12/2026
Dr Mifsud is fabulous! I travel from 1.5 hours away to see him specifically.
1/7/2026
Dr. Ayala is a competent & caring physician.
1/4/2026
I wish everyone received his type of care whenever seeing a medical professional. I will definitely recommend this practice
12/31/2025
I was blown away by Dr. Mifsud's positive attitude and energy. He explained things so very well!
12/12/2025
Couldn't be better
12/10/2025
Excellent service
12/10/2025
I was in/out in less than 30 minutes. Terrific!
12/10/2025
I'M IN GOOD HANDS.
12/6/2025
Dr Mifsud took care to see that I understood everything that we discussed.
12/5/2025
Good
12/5/2025
Good
11/18/2025
Dr Mifsud is a to the point guy with very good bedside manners!
11/15/2025
Dr. Misfud is always excellent.
11/14/2025
Excellent doctor!!!
11/14/2025
I have been seeing DR Misfud for 6 years and he is always great.
11/13/2025
Dr. Mifsud is an exceptional doctor. He is extremely knowledgeable. He takes time and explains things clearly. He is always kind and puts my mind at ease with any concerns.
10/26/2025
He is just monitoring to ensure no growth
10/24/2025
Excellent!
9/26/2025
Dr Mifsud is very compassionate, he listened to my concerns, he treated me with respect. I am happy that he is my doctor
9/24/2025
Excellent experience
9/23/2025
Dr Mifsud is very compassionate, and listened to my concerns. He treated me with respect and friendship
9/21/2025
Great experience
9/18/2025
I appreciate the time she took to answer my questions fur our visit.
9/17/2025
The "After Visit Notes" were much less detailed than I receive at my Lee Health Physicians. I ended up having to do a "My Chart" request for information after receiving those notes.
9/12/2025
The PA was awesome and very knowledgeable. Dr.Mifsud blew me away. CLEARLY at the top of his game AND an amazing personality!?! Really? Yep I was shocked too but it's true! Loved loved loved him. Explained everything I needed to know very clearly and is very focused and committed to helping me. Thank you Dr.Mifsud and staff for making a fantastic visit out of what was an anxious unsure day for me! GO BULLS!
9/10/2025
The Dr was well versed in my case and this was obvious by the good and specific questions he asked me. This allowed the encounter to progress having needed information in order to create next steps.
9/7/2025
Good
9/4/2025
Explained the options, confirmed what he had Explained on the first visit.
9/3/2025
Dr. Mifsud is the best. Have always been pleased with him
9/3/2025
Very Professional!
8/27/2025
Great doctor to deal with
8/23/2025
I was very impressed with the entire team. They didn't treat me like a number. They were all very caring and explained details.
8/22/2025
Have recommended,
8/21/2025
One of the best doctors I've encountered.
8/21/2025
As aforesaid, I felt relief. Everyone was attentive and listened to my concerns regarding the possibility the cancer had spread.
8/14/2025
Dr. Misfud's care and compassion shines from him. Thank you.
8/14/2025
Excellent
8/13/2025
Dr Mifsud was very professional, communicated thoroughly and made me feel confident in his care
8/11/2025
Dr assistant and Dr mifsud very personalized explanation of surgery and treatment after we're done and easy to understand very perfessional felt at ease for surgery and glad to have him to do surgery thank you very much all
8/9/2025
Excellent doctor
8/8/2025
Good
8/3/2025
I came in with a concern, very little was explained on WHAT they were going to do (for example: she didn't explain that she was going to do with the camera, what it would feel like, what they would be looking for, etc. Wasn't impressed with their "bedside" manner.
8/3/2025
Good
7/30/2025
Dr Milsud is the best of the best!!!!
7/25/2025
Dr Misfud is great! He is fast and thorough. We will always be grateful for his help in saving my life!
7/21/2025
Top notch. Would highly recommend.
7/20/2025
Dr. Mifsud and the entire USF/ENT staff are phenomenal. Cancer patient early detection, long term treatment plan, plan implementation and execution (biopsy, pre-post CT scans, cancer treatment, all facets to fight the disease), overall plan monitoring and now post surveillance programs are world class. The entire team - life savers. I am very humble and grateful to be under their care. Nothing more to report. Thank you all very much.
7/17/2025
Great experience
7/14/2025
Dr. Midsuf and the entire USF/ENT staff are phenomenal. Cancer early detection patient, long term treatment plan, plan implementation and execution (biopsy, pre-post CT scans, cancer treatment, all facets to fight the disease), overall plan monitoring and now post surveillance programs are world class. The entire team - life savers. I am very humble and grateful to be under their care. Nothing more to report. Thank you all very much.
7/6/2025
Top Notch!
7/5/2025
I waited over an hour, there was no acknowledgement of my time and the fact that I was saw an hour past my appointment time. The providers were in the room for less than 5 minutes.
5/7/2025
Doctor as always very good
5/1/2025
Good
4/30/2025
Very competent and caring staff, and professionally courteous and friendly.
4/26/2025
Dr Misfud although very busy does take the time to answer my questions and that of my Family when they are with me.
4/25/2025
Everyone Is personable and caring.
4/24/2025
Dr Mifsud coordinated my care along with Dr.Arnaoutakis. Together they are seeing to my situation and upcoming surgery! I know I am in the most competent hand!!!
4/24/2025
Dr. Mifsud was courteous, professional, prompt and caring. I am very grateful for his care.

Insurance Coverage

Map & Directions

USF Health Department of Otolaryngology - Head and Neck Surgery

13330 USF Laurel DriveTampa, FL 33612
Monday - Friday

8:00 am - 5:00 pm

Saturday - Sunday

Closed

Fax