Matthew Mifsud, MD
Surgical Oncology, Head and Neck Surgical Oncology, Otolaryngology

4.8 out of 5,
New patient visits
USF Health Morsani Center for Advanced Healthcare
13330 Usf Laurel Drive,
Tampa, FL 33612
As a head and neck surgical oncologist, my major focus is the treatment within the head and neck region, affecting the face, neck, mouth and throat. At USF, I help lead a multidisciplinary team of medical professionals, that develop individualized cancer treatment plans, for each of our patients.
I have extensive surgical training and experience, which includes advanced subspecialization within my field of otolaryngology. This allows me to perform a wide array of surgical procedures and particularly focus on reconstructive surgery. This entails taking body parts from one area and transplanting them into the head and neck. This helps maintain a more normal physical appearance and optimizes speech/swallowing function, which can be impacted by cancer or other maladies. I'm able to not only treat a person's disease, but also help to optimize their quality of life long after treatment is complete.
In addition to cancer, I also focus on other complex head and neck conditions, such as those affecting the salivary glands, thyroid, and trachea. At USF, I also engage in various teaching and research activities, which enhance my ability to provide state-of-the-art care to all my patients.
I have extensive surgical training and experience, which includes advanced subspecialization within my field of otolaryngology. This allows me to perform a wide array of surgical procedures and particularly focus on reconstructive surgery. This entails taking body parts from one area and transplanting them into the head and neck. This helps maintain a more normal physical appearance and optimizes speech/swallowing function, which can be impacted by cancer or other maladies. I'm able to not only treat a person's disease, but also help to optimize their quality of life long after treatment is complete.
In addition to cancer, I also focus on other complex head and neck conditions, such as those affecting the salivary glands, thyroid, and trachea. At USF, I also engage in various teaching and research activities, which enhance my ability to provide state-of-the-art care to all my patients.
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Specialties
Head and Neck Surgical Oncology
Otolaryngology
Gender
Male
Languages
English
Age groups seen
Newborns (0-28 days)
Infants and Toddlers (ages 0-2)
Children (ages 3-11)
Adolescents (ages 12-18)
Adults
Geriatrics
Education
USF College of Medicine
Residency, Otolaryngology, 2015
University of Toronto Faculty of Medicine
Fellowship, Head & Neck Surgery, 2017
USF College of Medicine
Internship, Otolaryngology, 2011
Tufts University School of Medicine
Medical School, 2010
Boston College
Undergraduate, Biology, 2006
Certifications
American Board of Otolaryngology - Plastic Surgery Within the Head and Neck
American Board of Otolaryngology - Plastic Surgery Within the Head and Neck, 2016
Verified Reviews
The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
4.8 out of 5
303 ratings,
58 reviews
10/14/2026
Dr was excellent great communication
10/10/2026
Everything was great
10/9/2026
Very conscientious, professional
9/4/2026
I appreciated the outstanding care provided by Dr. Mifsud. His communication was clear, patient-centered, and consistent with my expectations for safe, high-quality ENT care. He took the time to explain my condition thoroughly, and the most helpful part of the visit was when he used the ultrasound images to show me the number of nodules in both thyroid lobes. He then discussed the care plan and scheduled me for a swallow test after I shared my concerns. I left the appointment feeling well informed, respected, and comfortable with the recommended course of action.
9/2/2026
Doctor Mifsud is great! I liked his attitude towards my cancer diagnosis and he made me, my family and friends feel at ease with my situation. I've been lucky that my PCPs have been like him as well. I wish all doctors were like him. Th world would be a better place.
9/2/2026
All good
8/19/2026
Provider explained my condition and treatment options in layman's terms.
8/12/2026
Love my physician/surgeon.
8/12/2026
Dr. Mifsud was very attentive and listened to all my concerns. He was knowledgeable and explained and answered all my questions. I feel like he truly cared about my medical situation and put my mind at ease. I had a wonderful experience with this doctor. Thank you.
8/7/2026
Answer my questions and was very helpful
8/2/2026
Dr. Misfud is an amazing doctor. He actually diagnosed our daughter while at a conference because the first place had no clue
7/29/2026
The doctor gave us so much information. Things I would never thought to ask. Very thorough visit.
7/27/2026
I had a lot of concerns and Dr Mifsud patiently responded to them all.
7/18/2026
Very good
7/15/2026
Dr. Mifsud is an incredible doctor whom I literally trust with my life.... His expertise is unmatched and I am blessed to have been assigned to his care
7/5/2026
Always good
6/28/2026
Dr. Mifsud treated me professionally and kindly. He explained everything to me clearly and took my concerns seriously.
6/2/2026
Very up front and clear in his explanations to me.
5/29/2026
Excellent Service by the Doctor and his staff
5/22/2026
The doc and team are great. My only feedback is to slowdown a little and listen a little more you almost can't finish what you are describing.
5/20/2026
Personal able, knowledgeable and engaging.
5/7/2026
From start to finish, outstanding medical care.
4/26/2026
Patiently answered all my questions and concerns.
4/23/2026
I recently transferred to Dr. Mifsud. I'm an very happy with the transition. Dr. Mifsud is fantastic and I hope to be with him for many years.
4/18/2026
Very impressed. Made me feel very comfortable
4/10/2026
Dr Mifsud is excellent he listens, evaluates and is precise ! He knew exactly what I needed even before he scoped me!
4/6/2026
Excellent
4/5/2026
My experience here was amazing! The doctor answered my questions about my health!
4/3/2026
Dr mifsud is awesome
3/28/2026
I finally found a Doctor Who listens to me. I had a plan in place and clear and concise was amazing with me and my husband and explain things to him as well. I felt so comfortable. I felt such a relief and strain and less stress and optimistic after my appointment.
3/15/2026
Good
3/13/2026
Dr spent maybe 5 mins with me.
3/12/2026
Good
2/28/2026
The medical doctor spent 5 mins in the room with me after a prolong wait and explained that he did not have "time" and I should not have been scheduled for a procedure (biopsy) on the first visit. The rheumatologist requested only a biopsy to rule out a medical disease. The nurse/tech confirmed prior to the doctor entering the room that my appt was for a biopsy. This decision to not perform the biopsy has delayed my care, completely disregarded the importance of my time and health because the doctor did not have time to do his job.
2/27/2026
Visit was fairly quick. No real concerns to discuss. Another followup visit in 6 months.
2/18/2026
Dr. Mifsud and his team are great. Always polite, always attentive.
2/18/2026
Dr. Mifsud is an outstanding doctor and is very helpful.
2/16/2026
Dr. Mifsud was so well-behaved, well-regarded, and very caring. Their attention was excellent.
2/13/2026
Dr. Matthew is honest and cares very much about his patients. Im very appreciative of him . Thanks
2/11/2026
Very good
1/31/2026
Both Dr. Mifsud and his PA explained everything from diagnosis and what would happen during surgery and post. Excellent job calming my fears
1/30/2026
Dr. Mifsud is, without a doubt, the most communicative doc I've ever visited. Clear answers, patient, a good listener, and clearly very smart. Highly recommend.
1/12/2026
Dr Mifsud is fabulous! I travel from 1.5 hours away to see him specifically.
1/7/2026
Dr. Ayala is a competent & caring physician.
1/4/2026
I wish everyone received his type of care whenever seeing a medical professional. I will definitely recommend this practice
12/31/2025
I was blown away by Dr. Mifsud's positive attitude and energy. He explained things so very well!
12/12/2025
Couldn't be better
12/10/2025
Excellent service
12/10/2025
I was in/out in less than 30 minutes. Terrific!
12/10/2025
I'M IN GOOD HANDS.
12/6/2025
Dr Mifsud took care to see that I understood everything that we discussed.
12/5/2025
Good
12/5/2025
Good
11/18/2025
Dr Mifsud is a to the point guy with very good bedside manners!
11/15/2025
Dr. Misfud is always excellent.
11/14/2025
Excellent doctor!!!
11/14/2025
I have been seeing DR Misfud for 6 years and he is always great.
11/13/2025
Dr. Mifsud is an exceptional doctor. He is extremely knowledgeable. He takes time and explains things clearly. He is always kind and puts my mind at ease with any concerns.
Insurance Coverage
Note:Please contact the practice directly to confirm your health plan is in network.
Aetna Better Health Medicaid & Healthy Kids
Aetna Medicare HMO-POS
Aetna Medicare PPO
Aetna/Coventry HMO,PPO and POS
AG Administrators
Ambetter - Exchange (Sunshine ACA Plan)
AvMed HMO
Beech Street
Blue Cross Blue Shield - Exchange Plans (ACA)
Blue Cross Blue Shield - Medicare Advantage HMO
Blue Cross Blue Shield - Medicare Advantage PPO
Blue Cross Blue Shield HMO-BlueCare (Health Options)
Blue Cross Blue Shield HMO-myBlue
Blue Cross Blue Shield HMO-SimplyBlue
Blue Cross Blue Shield Medicare Supplement-Advantage 65
Blue Cross Blue Shield PPO-NetworkBlue / BlueSelect
Blue Cross Blue Shield PPO-Preferred Patient Care (PPC)
Cigna HMO
Cigna PPO
Clear Health Alliance Medicaid (CHA)
CorVel PPO and Auto Medical
Curative PPO, EPO
Devoted Medicare HMO, PPO, D-SNP
Doctors Healthcare Plans Medicare HMO, D-SNP
Empath LIFE (PACE)
Employers Health Network (EHN)
Evolutions Prime PPO
Evolutions Traditional PPO
Florida Community Care (Medicaid)
Freedom Health Medicare HMO
Galaxy Health Network
HealthSpring Medicare HMO & PPO (fka Cigna Medicare)
Hillsborough County Health Care Plan (HCHCP)
Humana Healthy Horizons (Medicaid)
Humana Medicare HMO (Gold Plus)
Humana Medicare PPO
InnovAge (PACE)
Longevity Health Plan Medicare HMO, I-SNP
Molina Children's Medical Services (CMS)
Molina Marketplace (Exchange Plan)
Molina Medicaid
Molina Medicare Options Plus HMO SNP
MultiPlan PPO
Oscar Insurance Company of Florida
Pinellas County Sheriff's Office (PCSO)
Private Healthcare Systems PPO (PHCS)
Quality Health Management
School Insurance of Florida
Simply Healthcare Medicaid HMO and Healthy Kids
Simply Healthcare Medicare HMO
Solis Medicare HMO
Sunshine Health Medicaid HMO
TRICARE Prime (Humana Military)
TRICARE Prime Demo (CareSource Military & Veterans)
TRICARE Select (Humana Military)
Truli for Health
Ultimate Health Plans Medicare HMO
United Healthcare Commercial Plans
United Healthcare Exchange Plans
United Healthcare Medicaid
United Healthcare Medicare HMO and PPO
VA Community Care Network (Optum)
WellCare Medicare HMO
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Map & Directions
USF Health Morsani Center for Advanced Healthcare
13330 Usf Laurel DriveTampa, FL 33612
