Matthew Mifsud, MD

Surgical Oncology
Matthew Mifsud image
4.8 out of 5, 
New patient visits

USF Health Department of Otolaryngology - Head and Neck Surgery

13330 Usf Laurel Drive, Floor 3
Tampa, FL 33612
Fax
813-821-9702
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As a head and neck surgical oncologist, my major focus is the treatment within the head and neck region, affecting the face, neck, mouth and throat. At USF, I help lead a multidisciplinary team of medical professionals, that develop individualized cancer treatment plans, for each of our patients.





I have extensive surgical training and experience, which includes advanced subspecialization within my field of otolaryngology. This allows me to perform a wide array of surgical procedures and particularly focus on reconstructive surgery. This entails taking body parts from one area and transplanting them into the head and neck. This helps maintain a more normal physical appearance and optimizes speech/swallowing function, which can be impacted by cancer or other maladies. I'm able to not only treat a person's disease, but also help to optimize their quality of life long after treatment is complete.





In addition to cancer, I also focus on other complex head and neck conditions, such as those affecting the salivary glands, thyroid, and trachea. At USF, I also engage in various teaching and research activities, which enhance my ability to provide state-of-the-art care to all my patients.


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Verified Reviews

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
4.8 out of 5
302 ratings,
50 reviews
8/7/2026
Answer my questions and was very helpful
8/2/2026
Dr. Misfud is an amazing doctor. He actually diagnosed our daughter while at a conference because the first place had no clue
6/28/2026
Dr. Mifsud treated me professionally and kindly. He explained everything to me clearly and took my concerns seriously.
5/29/2026
Excellent Service by the Doctor and his staff
5/22/2026
The doc and team are great. My only feedback is to slowdown a little and listen a little more you almost can't finish what you are describing.
5/20/2026
Personal able, knowledgeable and engaging.
5/7/2026
From start to finish, outstanding medical care.
4/26/2026
Patiently answered all my questions and concerns.
4/23/2026
I recently transferred to Dr. Mifsud. I'm an very happy with the transition. Dr. Mifsud is fantastic and I hope to be with him for many years.
4/18/2026
Very impressed. Made me feel very comfortable
4/10/2026
Dr Mifsud is excellent he listens, evaluates and is precise ! He knew exactly what I needed even before he scoped me!
4/6/2026
Excellent
4/5/2026
My experience here was amazing! The doctor answered my questions about my health!
4/3/2026
Dr mifsud is awesome
3/28/2026
I finally found a Doctor Who listens to me. I had a plan in place and clear and concise was amazing with me and my husband and explain things to him as well. I felt so comfortable. I felt such a relief and strain and less stress and optimistic after my appointment.
3/15/2026
Good
3/13/2026
Dr spent maybe 5 mins with me.
3/12/2026
Good
2/28/2026
The medical doctor spent 5 mins in the room with me after a prolong wait and explained that he did not have "time" and I should not have been scheduled for a procedure (biopsy) on the first visit. The rheumatologist requested only a biopsy to rule out a medical disease. The nurse/tech confirmed prior to the doctor entering the room that my appt was for a biopsy. This decision to not perform the biopsy has delayed my care, completely disregarded the importance of my time and health because the doctor did not have time to do his job.
2/27/2026
Visit was fairly quick. No real concerns to discuss. Another followup visit in 6 months.
2/18/2026
Dr. Mifsud and his team are great. Always polite, always attentive.
2/18/2026
Dr. Mifsud is an outstanding doctor and is very helpful.
2/16/2026
Dr. Mifsud was so well-behaved, well-regarded, and very caring. Their attention was excellent.
2/13/2026
Dr. Matthew is honest and cares very much about his patients. Im very appreciative of him . Thanks
2/11/2026
Very good
1/31/2026
Both Dr. Mifsud and his PA explained everything from diagnosis and what would happen during surgery and post. Excellent job calming my fears
1/30/2026
Dr. Mifsud is, without a doubt, the most communicative doc I've ever visited. Clear answers, patient, a good listener, and clearly very smart. Highly recommend.
1/12/2026
Dr Mifsud is fabulous! I travel from 1.5 hours away to see him specifically.
1/7/2026
Dr. Ayala is a competent & caring physician.
1/4/2026
I wish everyone received his type of care whenever seeing a medical professional. I will definitely recommend this practice
12/31/2025
I was blown away by Dr. Mifsud's positive attitude and energy. He explained things so very well!
12/12/2025
Couldn't be better
12/10/2025
Excellent service
12/10/2025
I was in/out in less than 30 minutes. Terrific!
12/10/2025
I'M IN GOOD HANDS.
12/6/2025
Dr Mifsud took care to see that I understood everything that we discussed.
12/5/2025
Good
12/5/2025
Good
11/18/2025
Dr Mifsud is a to the point guy with very good bedside manners!
11/15/2025
Dr. Misfud is always excellent.
11/14/2025
Excellent doctor!!!
11/14/2025
I have been seeing DR Misfud for 6 years and he is always great.
11/13/2025
Dr. Mifsud is an exceptional doctor. He is extremely knowledgeable. He takes time and explains things clearly. He is always kind and puts my mind at ease with any concerns.
11/7/2025
I think Dr. Misfud is a great doctor, and I would recommend him to others.
10/26/2025
He is just monitoring to ensure no growth
10/24/2025
Excellent!
9/26/2025
Dr Mifsud is very compassionate, he listened to my concerns, he treated me with respect. I am happy that he is my doctor
9/24/2025
Excellent experience
9/23/2025
Dr Mifsud is very compassionate, and listened to my concerns. He treated me with respect and friendship
9/21/2025
Great experience

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Map & Directions

USF Health Department of Otolaryngology - Head and Neck Surgery

13330 Usf Laurel Drive, Floor 3 Tampa, FL 33612
Fax